Recurrent fever in newborns
Overview
Recurrent fever in newborns: Searching for infection
Recurrent, or periodic, fever is a condition characterized by repeated episodes of high temperature alternating with periods of normal well‑being. In newborns and infants in the first months of life this symptom is extremely concerning and always requires thorough medical evaluation to rule out hidden but serious infectious processes.
Why does the fever return?
Unlike older children, in whom recurrent fever may be a manifestation of benign autoinflammatory syndromes (e.g., PFAPA), in newborns physicians primarily look for a hidden source of infection that has not been fully treated or is chronic in nature.
Possible causes:
- Recurrent urinary tract infection (UTI): This is one of the most common causes. If the child has a congenital anomaly of the urinary system (e.g., vesicoureteral reflux), it can lead to repeated episodes of infection and fever.
- Congenital infections (TORCH complex): Some congenital infections, such as cytomegalovirus, can have a wave‑like course with periodic temperature spikes.
- Congenital immunodeficiencies: Defects in the immune system make the child vulnerable to repeated, often severe infections.
Diagnostic approach
If your newborn experiences repeated fever episodes, a comprehensive inpatient evaluation is required, which may include repeat blood and urine tests, ultrasound, and a consultation with an immunologist. If the cause cannot be identified, the condition may be classified as fever of unknown origin.
Related symptoms
High fever in newborns
High fever in newborns: Always a cause for concern Any increase in rectal temperature above 38.0°C in a child up to 3 months old is considered a potentially dangerous condition and…
Subfebrile temperature in newborns
Subfebrile temperature in newborns: Normal or problem? Subfebrile temperature is an elevation of body temperature in the range of 37.1°C to 38.0°C. In newborns this condition often…
Fever with Rash in Newborns
Fever with Rash in Newborns: "Red Flag" Combination of fever and rash in a child in the first months of life is always a reason to seek immediate medical attention. Although there …
Fever with seizures in newborns
Fever with seizures in newborns: Always dangerous The occurrence of seizures in a newborn (up to 3 months old), regardless of whether they have a fever, is always an emergency situ…
Fever of Unknown Origin in Newborns
Fever of Unknown Origin in Newborns Fever of unknown origin (FUO) — is a clinical situation in which the child has a prolonged fever (usually more than 1-2 weeks), the cause of whi…